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KMID : 0376319960080010041
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Dental Journal of CNU
1996 Volume.8 No. 1 p.41 ~ p.63
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An experimental reconstruction of discontinuous mandibular defect with freeze-dried demineralized allogeneic bone in rabbits
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Park Kwang
Chung Sung-Su
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Abstract
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This study was purposed to evaluate the mechanical effects and calcium contents of demineralized bone matrix on the repair of discontinuous mandibular defects in a rabbit model.
In experimental group Ⅰ, the 6 mm discontinuous bone defect was created in the mandibular body and then grafted with arutogenous iliac bone. In experimental group Ⅱ, the same bone defects was made and grafted with demineralized allogeneic bone.
The experimental animals were sacrified at 4 weeks and 8 weeks postoperatively. To evaluate the effects of autogenous and demineralized allogeneic bone graft on the discontinuous mandible, the biomechanical study to compare the mechnical strenths, and the degree of calcium contents by atomic absorption spectrometry were performed.
The biomechanical studies demonstrated that the bone induced by autogenous bone achieved 68% of normal bone and the demineralized allogeneic bone matrix bone(DABM) achieved 35% of normal bone at 8 weeks.
Atomic absorption spedtrometric study revealed that both the autogenous and demineralized bone demonstrated very small concetration of calcium at fourth weeks. However, there were gradual increase of calcium concentration after 8 weeks.
It showed that the autogenous grafts are worthy using in mandibular discontinuous defects, while demineralized allogeneic bone has some possibility to repair the discontinuous defects.
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KEYWORD
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